Dr. Candace Reno

Candace Reno, PhD

Professor of Molecular Biology
Medical Physiology Specialist
International Experience:  Mexico, USA

 

 

 

Education

  • Doctor of Philosophy, Molecular Cell Biology, Washington University in St. Louis, MO, USA
  • Master of Science, Biology, California State University, San Bernardino, CA, USA
  • Bachelor of Science, Biology, California State University, San Bernardino, CA, USA

Doctoral Dissertation 

  • Glucosensing, hypoglycemia, and the brain 

Master's Thesis 

  • The effects of leptin and thyroid hormone on metabolism and lipid trafficking in the liver and adipose tissue of ob/ob mice  

 

Academic Experience

  • Post-Doctoral Research Associate, Endocrinology, University of Utah, Salt Lake City, UT, USA
  • Post-Doctoral Fellow, Endocrinololgy, Yale University, New Haven, CT, USA
  • Adjunct Faculty, Science, Allied Health, and Engineering Division, Middlesex Community College, Middletown, CT, USA
  • Adjunct Faculty, Bioloigical Sciences, Quinnipicac University, Hamden, CT, USA
  • Teaching Assistant, Biology, Washington University in St. Louis, MO, USA
  • Laboratory Teacher, Biology, California State University, San Bernardino, CA, USA
  • Teaching Assistant, Biology, California State University, San Bernardino, CA, USA  
  • Graduate Research, Endocrinology, Metabolism, and Lipid Research, Washington University in St.Louis, MO, USA
  • Graduate Research, Leptin and Thyroid Hormone Regulation, California State University, San Bernardino, CA, USA

 

Teaching Specializations

  • Physiology & Anatomy
  • Neuroscience
  • Marine Biology, Cell Biology
  • Biochemistry
  • General Biology 

Ministry & Professional Experience

  • Operation Christmas Child coordinator, Samaritan's Purse, Salt Lake City, UT
  • Open Water Scuba Instructor, Dive Utah, Holladay, UT
  • Assistant Scuba Instructor, Dive Utah, Holladay, UT
  • Assistant Scuba Instructor, Hamden Scuba, Hamden, CT

 

Presentations  

  • 2006 Oral presentation, West Coast Biological Sciences Undergraduate Research Competition, San Diego, CA - "24 hour metabolic analyses of FATP1 knockout mice"
  • 2007 Poster presentation, Federation of American Societies for Experimental Biology (FASEB), Washington, D.C. "Leptin and thyroid hormone regulate hepatic lipid trafficking into macro- and microvesicular pools"
  • 2010 Oral presentation, American Diabetes Association Scientific Sessions, Orlando, FL - "Brain specific glucose transporter 4 knockout mice display decreased brain glucose uptake and hepatic insulin resistance"
  • 2011 Oral presentation, American Diabetes Association Scientific Sessions, San Diego, CA - Deaths due to severe hypoglycemia are exacerbated by diabetes and ameliorated by hypoglycemic preconditioning
  • 2011 Oral presentation, American Diabetes Association- Diabetes and the Brain Symposium, Alexandria, VA - "Brain specific GLUT4 knockout mice have impaired glucose sensing"
  • 2012 Oral presentation, American Diabetes Association Scientific Sessions, Philadelphia, PA - "Adrenergic blockade prevents life threatening cardiac arrhythmias and sudden death due to severe hypoglycemia"
  • 2012 Invited talk, California State University, San Bernardino, Department of Biology Symposium - "Diabetes and its complications"
  • 2013 Oral presentation, American Diabetes Association Scientific Sessions, Chicago, IL - "Brain neuroglycopenia regulates cardiac arrhythmias and sudden death due to severe hypoglycemia"
  • 2014 Oral presentation, American Diabetes Association Scientific Sessions, San Francisco, CA - "Brain leptin infusion blunts the glucagon response to hypoglycemia"
  • 2015 Poster presentation, American Diabetes Association Scientific Sessions, Boston, MA - "Brain leptin infusion increases the glucagon response after recurrent hypoglycemia in normal rats"
  • 2016 University of Utah Seminars in Metabolism - "Preventing severe hypoglycemia-induced fatal cardiac arrhythmias"

 

Publications 

  • Yingjiang Zhou, Justin Lee, Candace M Reno, Cheng Sun, Sang Won Park, Jason Chung, Jaemin Lee, Simon J Fisher, Morris F White, Sudha B Biddinger and Umut Ozcan. Regulation of glucose homeostasis through a XBP-1-Fox01 interaction. Nature Medicine, 17 (3): 356- 365, March 2011.
  • Candace M Reno, Marina Litvin, Amy Clark, and Simon J Fisher. Defective counterregulation and hypoglycemia unawareness in diabetes: mechanisms and emerging treatments. Endocrinology and Metabolism Clinics of North America, 42(1): 15-38, March 2013.
  • Candace M Reno, Tariq Tanoli, Adam Bree, Dorit Daphna-Iken, Chen Cui, Susan E Maloney, David F Wozniak, and Simon J Fisher. Antecedent glycemic control reduces severe hypoglycemia- induced neuronal damage in diabetic rats. American Journal of Physiology- Endocrinology and Metabolism, 304 (12): E1331-1337, June 2013.
  • Candace M Reno, Dorit Daphna-Iken, Y. Stefanie Chen, Jennifer VanderWeele, Krishan Jethi, and Simon J Fisher. Severe hypoglycemia-induced lethal cardiac arrhythmias are mediated by sympathoadrenal activation. Diabetes, 62 (10): 3570- 3581, October 2013.
  • Candace M Reno, Yuyan Ding, and Robert Sherwin. Leptin acts in the brain to influence hypoglycemic counterregulation: Disparate effects of acute and recurrent hypoglycemia on glucagon release. American Journal of Physiology- Endocrinology and Metabolism, 309(12): E960-967, December 2015.
  • Candace M Reno, Erwin C Puente, Dorit Daphna-Iken, Zhenyu Sheng, Adam J Bree, Vanessa H Routh, Barbara B Kahn, and Simon J Fisher. Brain GLUT4 knockout mice have impaired glucose tolerance, decreased insulin sensitivity, and impaired hypoglycemic counterregulation. Diabetes. In press. 

 

Membership in Academic & Professional Societies

  • American Association of Anatomists
  • American Association of Diabetes
  • Phi Sigma Honor Society
  • Golden Key International Honor Society
  • Professional Association of Diving Instructors